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  1. Project Clover database Mon Nov 11 2024 15:05:32 GMT
  2. Package jalview.util

File ComparisonTest.java

 

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Classes

Class Line # Actions
ComparisonTest 36 123 11
1.0100%
 

Contributing tests

This file is covered by 9 tests. .

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1    /*
2    * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
3    * Copyright (C) $$Year-Rel$$ The Jalview Authors
4    *
5    * This file is part of Jalview.
6    *
7    * Jalview is free software: you can redistribute it and/or
8    * modify it under the terms of the GNU General Public License
9    * as published by the Free Software Foundation, either version 3
10    * of the License, or (at your option) any later version.
11    *
12    * Jalview is distributed in the hope that it will be useful, but
13    * WITHOUT ANY WARRANTY; without even the implied warranty
14    * of MERCHANTABILITY or FITNESS FOR A PARTICULAR
15    * PURPOSE. See the GNU General Public License for more details.
16    *
17    * You should have received a copy of the GNU General Public License
18    * along with Jalview. If not, see <http://www.gnu.org/licenses/>.
19    * The Jalview Authors are detailed in the 'AUTHORS' file.
20    */
21    package jalview.util;
22   
23    import static org.testng.AssertJUnit.assertEquals;
24    import static org.testng.AssertJUnit.assertFalse;
25    import static org.testng.AssertJUnit.assertTrue;
26   
27    import org.testng.annotations.BeforeClass;
28    import org.testng.annotations.BeforeMethod;
29    import org.testng.annotations.Test;
30   
31    import jalview.bin.Cache;
32    import jalview.datamodel.Sequence;
33    import jalview.datamodel.SequenceI;
34    import jalview.gui.JvOptionPane;
35   
 
36    public class ComparisonTest
37    {
38   
 
39  1 toggle @BeforeClass(alwaysRun = true)
40    public void setUpJvOptionPane()
41    {
42  1 JvOptionPane.setInteractiveMode(false);
43  1 JvOptionPane.setMockResponse(JvOptionPane.CANCEL_OPTION);
44    }
45   
 
46  9 toggle @BeforeMethod(alwaysRun = true)
47    public void loadProperties()
48    {
49  9 Cache.loadProperties("test/jalview/util/comparisonTestProps.jvprops");
50    }
51   
 
52  1 toggle @Test(groups = { "Functional" })
53    public void testIsGap()
54    {
55  1 assertTrue(Comparison.isGap('-'));
56  1 assertTrue(Comparison.isGap('.'));
57  1 assertTrue(Comparison.isGap(' '));
58  1 assertFalse(Comparison.isGap('X'));
59  1 assertFalse(Comparison.isGap('x'));
60  1 assertFalse(Comparison.isGap('*'));
61  1 assertFalse(Comparison.isGap('G'));
62    }
63   
64    /**
65    * Test for isNucleotide is that sequences in a dataset are more than 85%
66    * AGCTU. Test is not case-sensitive and ignores gaps.
67    */
 
68  1 toggle @Test(groups = { "Functional" })
69    public void testIsNucleotide_sequences()
70    {
71  1 SequenceI seq = new Sequence("eightypercent+fivepercent", "agctuagcPV");
72  1 assertFalse(Comparison.isNucleotide(new SequenceI[] { seq }));
73  1 assertFalse(
74    Comparison.isNucleotide(new SequenceI[][]
75    { new SequenceI[] { seq } }));
76   
77  1 seq = new Sequence("eightyfivepercent+tenpercent",
78    "agctuagcgVagctuagcuVE");
79  1 assertFalse(Comparison.isNucleotide(new SequenceI[] { seq }));
80   
81  1 seq = new Sequence(">nineyfivepercent+0percent",
82    "aagctuagcgEagctuagcua");
83  1 assertFalse(Comparison.isNucleotide(new SequenceI[] { seq }));
84   
85  1 seq = new Sequence("nineyfivepercent+0percent", "agctuagcgEagctuagcua");
86  1 assertFalse(Comparison.isNucleotide(new SequenceI[] { seq }));
87   
88  1 seq = new Sequence("nineyfivepercent+fivepercent",
89    "agctuagcgWagctuagcua");
90  1 assertTrue(Comparison.isNucleotide(new SequenceI[] { seq }));
91   
92  1 seq = new Sequence("nineyfivepercent+tenpercent",
93    "agctuagcgEWWctuagcua");
94  1 assertFalse(Comparison.isNucleotide(new SequenceI[] { seq }));
95   
96  1 seq = new Sequence("eightyfivepercent+fifteenpercent",
97    "agctuagcgWWWctuagcua");
98  1 assertFalse(Comparison.isNucleotide(new SequenceI[] { seq }));
99   
100  1 seq = new Sequence("eightyfivepercentgapped",
101    "--agc--tuA--GCPV-a---gct-uA-GC---UV");
102  1 assertFalse(Comparison.isNucleotide(new SequenceI[] { seq }));
103   
104  1 seq = new Sequence("ninetyfivepercentgapped",
105    "ag--ct-u-a---gc---g----aag--c---tuagcuV");
106  1 assertTrue(Comparison.isNucleotide(new SequenceI[] { seq }));
107   
108  1 seq = new Sequence("allgap", "---------");
109  1 assertFalse(Comparison.isNucleotide(new SequenceI[] { seq }));
110   
111  1 seq = new Sequence("DNA", "ACTugGCCAG");
112  1 SequenceI seq2 = new Sequence("Protein", "FLIMVSPTYW");
113    /*
114    * 90% DNA but one protein sequence - expect false
115    */
116  1 assertFalse(
117    Comparison.isNucleotide(new SequenceI[]
118    { seq, seq, seq, seq, seq, seq, seq, seq, seq, seq2 }));
119  1 assertFalse(
120    Comparison.isNucleotide(new SequenceI[][]
121    { new SequenceI[] { seq }, new SequenceI[] { seq, seq, seq },
122    new SequenceI[]
123    { seq, seq, seq, seq, seq, seq2 } }));
124    /*
125    * 80% DNA but one protein sequence - Expect false
126    */
127  1 assertFalse(
128    Comparison.isNucleotide(new SequenceI[]
129    { seq, seq, seq, seq, seq, seq, seq, seq, seq2, seq2 }));
130  1 assertFalse(
131    Comparison.isNucleotide(new SequenceI[][]
132    { new SequenceI[] { seq }, new SequenceI[] { seq, seq, seq },
133    new SequenceI[]
134    { seq, seq, seq, seq, seq2, seq2, null } }));
135   
136  1 String seqString = "aaatatatatgEcctgagtcgt";
137  1 seq = new Sequence("ShortProteinThatLooksLikeDNA", seqString);
138  1 assertFalse(Comparison.isNucleotide(new SequenceI[] { seq }));
139  1 seq = new Sequence("LongProteinThatLooksLikeDNA", seqString.repeat(10));
140  1 assertTrue(Comparison.isNucleotide(new SequenceI[] { seq }));
141   
142  1 assertFalse(Comparison.isNucleotide((SequenceI[]) null));
143  1 assertFalse(Comparison.isNucleotide((SequenceI[][]) null));
144    }
145   
146    /**
147    * Test the percentage identity calculation for two sequences
148    */
 
149  1 toggle @Test(groups = { "Functional" })
150    public void testPID_includingGaps()
151    {
152  1 String seq1 = "ABCDEFG"; // extra length here is ignored
153  1 String seq2 = "abcdef";
154  1 assertEquals("identical", 100f, Comparison.PID(seq1, seq2), 0.001f);
155   
156    // comparison range defaults to length of first sequence
157  1 seq2 = "abcdefghijklmnopqrstuvwxyz";
158  1 assertEquals("identical", 100f, Comparison.PID(seq1, seq2), 0.001f);
159   
160    // 5 identical, 2 gap-gap, 2 gap-residue, 1 mismatch
161  1 seq1 = "a--b-cdefh";
162  1 seq2 = "a---bcdefg";
163  1 int length = seq1.length();
164   
165    // match gap-residue, match gap-gap: 9/10 identical
166    // TODO should gap-gap be included in a PID score? JAL-791
167  1 assertEquals(90f, Comparison.PID(seq1, seq2, 0, length, true, false),
168    0.001f);
169    // overloaded version of the method signature above:
170  1 assertEquals(90f, Comparison.PID(seq1, seq2), 0.001f);
171   
172    // don't match gap-residue, match gap-gap: 7/10 identical
173    // TODO should gap-gap be included in a PID score?
174  1 assertEquals(70f, Comparison.PID(seq1, seq2, 0, length, false, false),
175    0.001f);
176    }
177   
 
178  1 toggle @Test(groups = { "Functional" })
179    public void testIsNucleotide()
180    {
181  1 assertTrue(Comparison.isNucleotide('a'));
182  1 assertTrue(Comparison.isNucleotide('A'));
183  1 assertTrue(Comparison.isNucleotide('c'));
184  1 assertTrue(Comparison.isNucleotide('C'));
185  1 assertTrue(Comparison.isNucleotide('g'));
186  1 assertTrue(Comparison.isNucleotide('G'));
187  1 assertTrue(Comparison.isNucleotide('t'));
188  1 assertTrue(Comparison.isNucleotide('T'));
189  1 assertTrue(Comparison.isNucleotide('u'));
190  1 assertTrue(Comparison.isNucleotide('U'));
191  1 assertFalse(Comparison.isNucleotide('-'));
192  1 assertFalse(Comparison.isNucleotide('P'));
193    }
194   
 
195  1 toggle @Test(groups = { "Functional" })
196    public void testIsNucleotideAmbiguity()
197    {
198  1 assertTrue(Comparison.isNucleotide('b', true));
199  1 assertTrue(Comparison.isNucleotide('B', true));
200  1 assertTrue(Comparison.isNucleotide('d', true));
201  1 assertTrue(Comparison.isNucleotide('V', true));
202  1 assertTrue(Comparison.isNucleotide('M', true));
203  1 assertTrue(Comparison.isNucleotide('s', true));
204  1 assertTrue(Comparison.isNucleotide('W', true));
205  1 assertTrue(Comparison.isNucleotide('x', true));
206  1 assertTrue(Comparison.isNucleotide('Y', true));
207  1 assertTrue(Comparison.isNucleotide('r', true));
208  1 assertTrue(Comparison.isNucleotide('i', true));
209  1 assertFalse(Comparison.isNucleotide('-', true));
210  1 assertFalse(Comparison.isNucleotide('n', true));
211  1 assertFalse(Comparison.isNucleotide('P', true));
212    }
213   
214    /**
215    * Test the percentage identity calculation for two sequences
216    */
 
217  1 toggle @Test(groups = { "Functional" })
218    public void testPID_ungappedOnly()
219    {
220    // 5 identical, 2 gap-gap, 2 gap-residue, 1 mismatch
221    // the extra length of seq1 is ignored
222  1 String seq1 = "a--b-cdefhr";
223  1 String seq2 = "a---bcdefg";
224  1 int length = seq1.length();
225   
226    /*
227    * As currently coded, 'ungappedOnly' ignores gap-residue but counts
228    * gap-gap. Is this a bug - should gap-gap also be ignored, giving a PID of
229    * 5/6?
230    *
231    * Note also there is no variant of the calculation that penalises
232    * gap-residue i.e. counts it as a mismatch. This would give a score of 5/8
233    * (if we ignore gap-gap) or 5/10 (if we count gap-gap as a match).
234    */
235    // match gap-residue, match gap-gap: 7/8 identical
236  1 assertEquals(87.5f, Comparison.PID(seq1, seq2, 0, length, true, true),
237    0.001f);
238   
239    // don't match gap-residue with 'ungapped only' - same as above
240  1 assertEquals(87.5f, Comparison.PID(seq1, seq2, 0, length, false, true),
241    0.001f);
242    }
243   
 
244  1 toggle @Test(groups = { "Functional" })
245    public void testIsNucleotideSequence()
246    {
247  1 assertFalse(Comparison.isNucleotideSequence(null, true));
248  1 assertTrue(Comparison.isNucleotideSequence("", true));
249  1 assertTrue(Comparison.isNucleotideSequence("aAgGcCtTuU", true));
250  1 assertTrue(Comparison.isNucleotideSequence("aAgGcCtTuU", false));
251  1 assertFalse(Comparison.isNucleotideSequence("xAgGcCtTuU", false));
252  1 assertFalse(Comparison.isNucleotideSequence("aAgGcCtTuUx", false));
253  1 assertTrue(Comparison.isNucleotideSequence("a A-g.GcCtTuU", true));
254  1 assertFalse(Comparison.isNucleotideSequence("a A-g.GcCtTuU", false));
255  1 assertFalse(Comparison.isNucleotideSequence("gatactawgataca", false));
256    // including nucleotide ambiguity
257  1 assertTrue(
258    Comparison.isNucleotideSequence("gatacaWgataca", true, true));
259  1 assertFalse(
260    Comparison.isNucleotideSequence("gatacaEgataca", true, true));
261   
262    // not quite all nucleotides and ambiguity codes
263  1 Sequence seq = new Sequence("Ambiguity DNA codes", "gatacagatacabve");
264  1 assertFalse(Comparison.isNucleotide(seq));
265    // all nucleotide and nucleotide ambiguity codes
266  1 seq = new Sequence("Ambiguity DNA codes", "gatacagatacabvt");
267  1 assertFalse(Comparison.isNucleotide(seq));
268  1 seq = new Sequence("Ambiguity DNA codes", "agatacabb");
269  1 assertFalse(Comparison.isNucleotide(seq));
270    // 55% nucleotide with only Xs or Ns
271  1 assertTrue(Comparison
272    .isNucleotide(new Sequence("dnaWithXs", "gatacaXXXX")));
273  1 assertTrue(Comparison
274    .isNucleotide(new Sequence("dnaWithXs", "gatacaNNNN")));
275  1 assertFalse(Comparison
276    .isNucleotide(new Sequence("dnaWithXs", "gatacXXXXX")));
277  1 assertFalse(Comparison
278    .isNucleotide(new Sequence("dnaWithXs", "gatacNNNNN")));
279    }
280   
 
281  1 toggle @Test(groups = { "Functional" })
282    public void testIsSameResidue()
283    {
284  1 assertTrue(Comparison.isSameResidue('a', 'a', false));
285  1 assertTrue(Comparison.isSameResidue('a', 'a', true));
286  1 assertTrue(Comparison.isSameResidue('A', 'a', false));
287  1 assertTrue(Comparison.isSameResidue('a', 'A', false));
288   
289  1 assertFalse(Comparison.isSameResidue('a', 'A', true));
290  1 assertFalse(Comparison.isSameResidue('A', 'a', true));
291    }
292   
 
293  1 toggle @Test(groups = { "Functional" })
294    public void testNucleotideProportion()
295    {
296  1 assertFalse(Comparison.myShortSequenceNucleotideProportionCount(2, 3));
297  1 assertTrue(Comparison.myShortSequenceNucleotideProportionCount(3, 3));
298  1 assertFalse(Comparison.myShortSequenceNucleotideProportionCount(2, 4));
299  1 assertTrue(Comparison.myShortSequenceNucleotideProportionCount(3, 4));
300  1 assertFalse(
301    Comparison.myShortSequenceNucleotideProportionCount(17, 20));
302  1 assertTrue(Comparison.myShortSequenceNucleotideProportionCount(18, 20));
303  1 assertFalse(
304    Comparison.myShortSequenceNucleotideProportionCount(38, 50));
305  1 assertTrue(Comparison.myShortSequenceNucleotideProportionCount(39, 50));
306  1 assertFalse(
307    Comparison.myShortSequenceNucleotideProportionCount(54, 100));
308  1 assertTrue(
309    Comparison.myShortSequenceNucleotideProportionCount(55, 100));
310    }
311    }